tert-butyl N-[[(2S)-pyrrolidin-2-yl]methyl]carbamate
(S)-2-N-BOC-Aminomethylpyrrolidine
CAS: 141774-70-1
Molecular Formula: C10H20N2O2
tert-butyl N-[[(2S)-pyrrolidin-2-yl]methyl]carbamate - Names and Identifiers
tert-butyl N-[[(2S)-pyrrolidin-2-yl]methyl]carbamate - Physico-chemical Properties
| Molecular Formula | C10H20N2O2 |
| Molar Mass | 200.28 |
| Density | 0.997 |
| Boling Point | 303.9±15.0 °C(Predicted) |
| Flash Point | 137.6°C |
| Vapor Presure | 0.000902mmHg at 25°C |
| pKa | 12.58±0.46(Predicted) |
| Refractive Index | 1.46 |
tert-butyl N-[[(2S)-pyrrolidin-2-yl]methyl]carbamate - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
tert-butyl N-[[(2S)-pyrrolidin-2-yl]methyl]carbamate - Introduction
S-2-BOC-Aminomethylpyrrolidine is an organic compound whose chemical structure contains an aminomethyl group and a pyrrole ring. The following is a description of the properties, uses, preparation and safety information of S-2-BOC-aminomethylpyrrolidine:
Properties: S-2-BOC-Aminomethylpyrrolidine is a colorless liquid, soluble in common organic solvents such as ethanol and dimethylformamide. It has a lower boiling point and a higher melting point. It is an unstable compound that is easily oxidized in open air.
Purpose: S-2-BOC-aminomethylpyrrolidine is an important intermediate compound, which is widely used in organic synthesis. It can be used in the synthesis of pyrroline, pyridine, oxazine compounds. In addition, it can be used as a protecting group or an aminating reagent in the synthesis of drugs.
Preparation method: S-2-BOC-aminomethylpyrrolidine is usually prepared by reacting 2-BOC-aminomethylpyrrolidine with an appropriate amount of catalyst under suitable reaction conditions. The reaction is generally carried out under an inert atmosphere to prevent oxidation.
Safety information: S-2-BOC-aminomethylpyrrolidine is a chemical that requires attention to safety measures during handling. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, suitable personal protective equipment, such as gloves and protective glasses, should be worn during contact. At the same time, it should be operated in a well-ventilated place and avoid direct exposure to open flames or high temperatures.
Properties: S-2-BOC-Aminomethylpyrrolidine is a colorless liquid, soluble in common organic solvents such as ethanol and dimethylformamide. It has a lower boiling point and a higher melting point. It is an unstable compound that is easily oxidized in open air.
Purpose: S-2-BOC-aminomethylpyrrolidine is an important intermediate compound, which is widely used in organic synthesis. It can be used in the synthesis of pyrroline, pyridine, oxazine compounds. In addition, it can be used as a protecting group or an aminating reagent in the synthesis of drugs.
Preparation method: S-2-BOC-aminomethylpyrrolidine is usually prepared by reacting 2-BOC-aminomethylpyrrolidine with an appropriate amount of catalyst under suitable reaction conditions. The reaction is generally carried out under an inert atmosphere to prevent oxidation.
Safety information: S-2-BOC-aminomethylpyrrolidine is a chemical that requires attention to safety measures during handling. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, suitable personal protective equipment, such as gloves and protective glasses, should be worn during contact. At the same time, it should be operated in a well-ventilated place and avoid direct exposure to open flames or high temperatures.
Last Update：2024-04-09 21:11:58
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